slow release pentoxifylline and captopril could prevent delayed pulmonary complications of mustard gas in animal models
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منابع مشابه
Histopathological study of delayed Mustard Gas Keratopathy
Aims: Ocular injury by mustard gas (HD) leads to severe eye damage. Long term characterization of mustard gas ocular toxicity has not been described in detail yet. Present study was performed in order to explore chronic histological and immunopathologic effects of HD ocular exposure and try to find etiology for these effects. Methods: This descriptive case study was performed on corneal and...
متن کاملcorrelation of delayed mustard gas ocular complications with severity of skin, respiratory, hematologic, and immunologic complications
purpose: to determine any possible correlation between delayed ocular complications with late-onset complications of mustard gas poisoning in other systems including skin, respiratory tract, and immunohematologic system. methods: the study was conducted on 40 chemical war victims in khorasan province, iran. ophthalmologic and dermatologic examinations and spirometry were performed for all patie...
متن کاملDelayed ocular complications of mustard gas poisoning and the relationship with respiratory and cutaneous complications.
BACKGROUND This study was aimed to determine the correlation between ocular complications and respiratory or cutaneous complications in a group of 40 Iranian veterans with late complications of sulphur mustard (SM) poisoning. METHODS Thorough ophthalmologic examination was performed on all severely SM-poisoned veterans in the province of Khorasan, Iran. Spirometric evaluation of pulmonary fun...
متن کاملPentoxifylline improves pulmonary gas exchange.
Pentoxifylline is a xanthine derivative with hemorrheologic and vascular properties that may improve gas exchange in patients with chronic obstructive pulmonary disease (COPD). We tested this hypothesis in 12 patients with COPD (mean FEV1 = 40 percent predicted; mean DCO, 8.6 ml/min/mm Hg) randomly divided into a treatment and control group and six healthy volunteers. Following establishment of...
متن کاملEvaluation of JAK2 (V617F) Mutation in Iranian Veterans with Delayed Complications of Sulphur Mustard Poisoning
Background: Sulfur mustard was the most widely applied chemical warfare agent by the Iraqi army in Iran–Iraq war (1983-1988). Considering the role of sulfur mustard toxicity in hematopoietic neoplasms and also new role of JAK2 mutation in these neoplasms, we assessed this mutation and delayed hematologic complications in veterans exposed to sulfur mustard. Methods: This case control st...
متن کاملA Mouse Model of Acute and Delayed Complications of Sulfur Mustard Analogue, 2-Chloroethyl Ethyl Sulfide
Background: Numerous studies have been conducted on humans, animals, and cell cultures exposed to Sulfur Mustard (SM). However, the precise mechanism and cause or long-term pattern of SM injuries are not well defined. There is no protocol available for treating people with severe eye, lung, and skin ailments. The current study aimed to develop an animal model of the acute and delayed complicati...
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عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
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